Frailty, an age-associated clinical syndrome, has a huge negative influence on physiological functions and disease outcome in the diabetic patients. The incidence of frailty with diabetes is rising. Therefore, frailty management in diabetes is a long-term and ongoing progress, in which exercise intervention plays a prominent role. However, exercise programs for frail diabetic adult differ greatly. This article reviews nursing, preventive medications, methods and the theoretical basis of exercise intervention for diabetic patients with frailty and points out the problems in current research. It aims to cause scholars and medical staff in China to ponder upon the frailty management of diabetic patients and to provide a reference for the construction of local exercise programs for frailty in diabetes.