Abstract:In recent years, the research on the correlation between chronic heart failure (CHF) and sarcopenia has become a hot topic in geriatrics. CHF patients can present loss of peripheral skeletal muscle in the early stage of the disease, resulting in a decline in physical activity. Evidence showed that CHF patients have significantly higher prevalence of sarcopenia than healthy age-matched individuals. CHF may cause sarcopenia through a variety of pathophysiological means, such as malnutrition, inflammation, hormone changes, oxidative stress and cell autophagy and apoptosis, etc. At the same time, sarcopenia exerts serious impact on the progression and prognosis of CHF. In addition, since the clinical manifestations of sarcopenia are not obvious, once patients experience symptoms, it usually indicates a significant decline in muscle mass and function. Therefore, it is essential for early screening for sarcopenia in CHF patients and then timely intervention. In this article, we focused on sarcopenia screening and reviewed the diagnosis and treatment of CHF complicated with sarcopenia.