Pyroptosis is a new type of programmed apoptosis of cells. During pyroptosis, the cell membrane bursts due to the stimulation of external factors, the cell begins to expand, cellular fluid flows out through the pores, inflammatory factors are generated to trigger inflammation, and the cell collapses in the later stage. Pyroptosis has been studied in the fields of neurosystemic diseases, infectious diseases, autoimmune diseases, and cardiovascular diseases. This article reviews the latest research findings of pyroptosis based on its mechanism, its role in cerebral hemorrhage and some key factors, to further explore the pathological mechanism of cerebral hemorrhage, hoping to provide a new approach to the research and treatment of cerebral hemorrhage.