慢性心力衰竭患者并发肌少症的机制及其运动疗法的研究进展
作者:
作者单位:

(1. 上海健康医学院康复学院,上海201318;2. 天津体育学院社会体育与健康科学学院,天津301617)

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R541.6

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国家自然科学基金(82172552)


Progress research on pathogenesis and exercise treatment of chronic heart failure in patients complicated with sarcopenia
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(1. College of Rehabilitation Sciences, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China;2. College of Exercise and Health Sciences, TianJin University of Sport, Tianjin 301617, China)

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    摘要:

    肌少症是老年慢性心力衰竭患者的常见并发症,也是影响患者预后的重要危险因素之一。近年来研究表明营养不良、身体活动不足、低肌血流量、炎症、激素改变、泛素-蛋白酶体系统、自噬、细胞凋亡及氧化应激等参与了老年慢性心力衰竭患者肌少症的病理过程,而运动疗法是其有效治疗途径,故本文对此进行综述,以期为临床医务工作者提供参考经验。

    Abstract:

    Sarcopenia is a common complication of elderly patients with chronic heart failure and one of the most important risk factors affecting the prognosis of patients. Research studies in recent years indicate that malnutrition, physical inactivity, low muscle blood flow, inflammation, hormonal changes, ubiquitin proteasome system, autophagy, apoptosis and oxidative stress play roles in the pathogenesis of sarcopenia induced by chronic heart failure, and exercise therapy is the effective treatment way. The research progress of these fields was reviewed in this paper, hoping to provide reference experience for clinical medical workers.

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侯国珍,郭琪,韩佩佩.慢性心力衰竭患者并发肌少症的机制及其运动疗法的研究进展[J].中华老年多器官疾病杂志,2022,21(5):370~374

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  • 收稿日期:2021-01-18
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  • 在线发布日期: 2022-05-30
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