Objective To observe the effects of integrated interventions on muscle mass, physical functions, and quality of life in the elderly individuals with possible sarcopenia in a community hospital. Methods A total of 64 elderly individuals with possible sarcopenia were randomly divided into control group (CON group, n=30) and integrated intervention group (INT group, n=34). The CON group received complication management and health education, and the INT group received integrated interventions of medication, exercise and nutrition. After 12 weeks, the effects of intervention were observed on the calf circumference, upper limb grip strength, body composition, physical function and self-assessment of healthy behaviors in the two groups. SPSS statistics 23.0 was used for data analysis. Depending on the data type, t-test, rank-sum test, or χ² test were used for comparison between groups. Results Compared with the same group before intervention and the CON group after intervention, the INT group had lower body fat percentage, higher muscle mass of upper or lower limbs and calf circumferences, stronger grip strength, and shorter timed up and go (TUG) duration, and the differences were statistically significant (P<0.05 ). There was no significant changes in the indexes of CON group before and after intervention (P＞0.05). Conclusion The integrated interventions can improve muscle mass, muscle strength and physical functions of the elderly with possible sarcopenia, thus reducing sarcopenia occurrence and enhancing their quality of life.