Shenxian Shengmai (SXSM) oral liquid is a Chinese patent medicine with proven curative efficacy and safety. Evidence from modern pharmacological studies with various animals and cells show that SXSM can accelerate the heart rate and improve the clinical symptoms of patients with bradycardia by increasing the concentration of cyclic adenosine monophosphate in cells, promoting the opening of calcium channels, improving the degree of pathological damage, delaying fibrosis of sinus node in patients with sick sinus syndrome, increasing I_f current and regulating gene expression. A large number of clinical studies have shown that SXSM has a better efficacy on heart rate improvement than other traditional Chinese patent medicines and western medicines that increase heart rate.