Nutrients are substances that maintains life activities by being obtained from food through digestion, absorption and metabolism. Recent studies have shown that some of these nutrients play important roles in immunity regulation, anti-fatigue, sleep regulation and other aspects in addition to maintenance of life activities. Improving the immunity of the body is of great benefit to resist the invasion of viruses, bacteria and other microorganisms. This paper reviews the research progress of immune-enhancing nutrients in order to provide reference for the correct selection of immune-enhancing agents.