The elderly are the vulnerable population of chronic kidney disease (CKD). Aging, comorbidities, polypharmacy are risk factors for poor prognosis of CKD. The elderly CKD patients are inclined to develop sarcopenia due to chronic inflammation, protein energy wasting, and reduced exercises. The adverse effect of sarcopenia on their prognosis has attracted the attention of nephrologists and geriatricians. Sarcopenia may increase incidence of cardiovascular events and all-cause mortality in the elderly CKD patients, which is closely associated with the poor prognosis of elderly CKD patients.