Hypertension is an important factor affecting the health of the elderly. Antihypertensive treatment can reduce the risk of stroke, cardiovascular events, and death in elderly hypertensive patients. Frailty often coexists with hypertension in elderly population, but few studies have focused on hypertension and frailty in the elderly. More importantly, conclusions vary in the studies about the antihypertensive treatment in elderly hypertensive patients with frailty. Still controversy are the starting values and target values of, the benefits from, and the strategies of the antihypertensive treatment in those patients. Therefore, this article reviews the antihypertensive treatment in elderly hypertensive patients with frailty.