【Abstract】Coronary CT angiography (CCTA) can be employed to assess the anatomical stenosis of the coronary artery but is unable to accurately determine whether the stenosis, especially borderline ones, can cause the myocardial ischemia. Fractional flow reserve (FFR) is a gold standard for assessing functional ischemia as a result of coronary stenosis, but it′s invasive and expensive, so it has not been widely used in clinical practice. The fractional flow reserve based on coronary CT (FFRCT), a non-invasive combination of function and anatomy, is of great significance for the diagnosis of coronary heart disease. This article reviews the value and clinical progress of FFRCT in the diagnosis of coronary heart disease.