Abstract:Objective To investigate the relationship of the severity of coronary heart disease (CHD) with blood glucose and carotid plaque. Methods From December 2015 to November 2018,8 non-diabetic patients with suspected CHD admitted to our hospital were selected and divided into CHD group (n=170) and non-CHD group (n=98) according to the results of coronary angiography. According to the Gensini score, the CHD patients were divided into mild group (n=53), moderate group (n=72) and severe group (n=45). An analysis was made of the relationship between the severity of coronary heart disease and fasting blood glucose (FPG) and carotid plaque. Statistical analysis was performed using SPSS statistics 20.0. Measurement data were expressed as mean±standard deviation ([AKx-D]±s), and t-test or analysis of variance was used for comparison between groups. Numeration data were expressed as number of cases (%). Inter-group comparison was performed using χ2 test. Logistic regression analysis was used to identify risk factors for CHD, and Pearson correlation analysis was performed for relationship of the severity of CHD with blood glucose and carotid plaque in patients. Results The FBG level [(6.41±2.46)mmol/L], the number of plaques (1.86±1.12), the carotid sclerosis level score (2.16±1.32), and the Crouse score (1.92±1.63) in the CHD group were significantly higher than those in the non-CHD group [(5.06±1.21)mmol/L, 0.53±0.61,0.38±0.55,0.66±0.57; P<0.05]. The FPG level [(6.82±1.67)mmol/L], number of plaques (2.93±1.24), carotid sclerosis grade (3.57±1.46) and Crouse score (3.87±2.24) in severe CHD group were significantly higher than those in the moderate [(6.15±1.58)mmol/L, 1.64±1.72,1.82±0.64,2.13±0.85] and mild CHD group [(5.67±1.34)mmol/L, 0.67±0.69,0.73±0.51,0.96±0.62], and the moderate CHD group was significantly higher than the mild CHD group (P<0.05). Regression analysis showed that FPG level, carotid atherosclerosis grading score, Crouse score were risk factors for CHD, and that Gensini scores of CHD were positively correlated with FPG level, carotid atherosclerosis score, and Crouse score. Conclusion The FPG level, plaque number, carotid atherosclerosis score and Crouse score in elderly patients with CHD are significantly higher than in those with suspected CHD. FPG level, carotid atherosclerosis score and Crouse score are independent risk factors for CHD, having a positive correlation with CHD Gensini score and playing an important role in the prediction and assessment of CHD.