Frailty is a complex age-related syndrome that can lead to reduced anti-stress capacity and ability to maintain homeostasis in the elderly and is associated with adverse outcomes such as falls, disability, and mortality. Cardiovascular diseases have a high incidence in the elderly population, and more and more studies have found that frailty and cardiovascular diseases are closely associated, and frailty can affect the prognosis of many cardiovascular diseases such as heart failure and hypertension. Therefore, clinicians should fully understand the relationship between frailty and cardiovascular diseases and the effect of frailty on the prognosis of cardiovascular diseases in clinical practice, which will be helpful to better disease management strategies in order to effectively postpone or avoid adverse outcomes.