Coronary artery calcification is a specific sign and an independent predictor for coronary atherosclerosis heart disease. Its mechanism is quite complicated, and is closely associated with gene, age, sex, personality, smoking, sleep, hypertension, hyperglycemia, hyperlipidemia, renal diseases, and so on. Early prediction and slowing the progression of coronary artery calcification are long-term, arduous task for diagnosis and treatment of coronary atherosclerosis heart disease in the future.