支气管肺泡灌洗治疗老年重症肺炎的临床疗效观察
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Clinical efficiency of bronchoalveolar lavage in the treatment of severe pneumonia in elderly patients
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    摘要:

    目的 探讨支气管肺泡灌洗(BAL)治疗老年重症肺炎的临床效果。方法 选取于2011年1月至2015年3月辽宁省金秋医院呼吸内科收治的老年重症肺炎患者82例,随机分为观察组和对照组(各41例)。对照组患者接受正常的呼吸内科治疗,观察组患者在此基础上加用纤维支气管镜下BAL。对比两组患者的临床疗效、动脉血气分析指标及急性生理学及慢性健康状况评分Ⅱ(APACHEⅡ)。结果 治疗7d后,观察组患者治疗总有效率明显高于对照组(87.8% vs 63.4%,P<0.05)。治疗3d后,两组患者APACHEⅡ评分及血氧饱和度(SaO2)、血氧分压(PaO2)、血二氧化碳分压(PaCO2)水平均较治疗前改善(P<0.05);且观察组比对照组的效果更明显(P<0.05)。结论 BAL辅助治疗可有效改善临床疗效,降低老年患者死亡率。

    Abstract:

    Objective To determine the curative effect of bronchoalveolar lavage (BAL) on severe pneumonia in the elderly patients. Methods A total of 82 elderly patients suffering from severe pneumonia in Department of Respiratory Diseases in our hospital from January 2011 to March 2015 were prospectively recruited in this study, and they were randomized into 2 groups, observation group [n=41, (76.7±8.8) years old] and control group [n=41, (76.3±9.3) years old]. The former group was treated by conventional treatment and BAL, while the latter by conventional treatment only. Their clinical outcomes, indices of arterial blood gas analysis, and scores of acute physiology and chronic health evaluation Ⅱ (APACHEⅡ) were compared between the 2 groups. Results In 7d after the treatment, the total effective rate was significantly higher in observation group than in the control group (87.8% vs 63.4%, P<0.05). The levels of oxygen saturation (SaO2), partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2) and APACHEⅡ scores were significantly improved in the 2 groups after 3 days’ treatment, and the improvement was more obvious in the observation group than in the control group (P<0.05). Conclusion BAL as an adjuvant treatment significantly improves curative effect and reduces mortality in the elderly patients with severe pneumonia.

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倪 楠*,林 琳.支气管肺泡灌洗治疗老年重症肺炎的临床疗效观察[J].中华老年多器官疾病杂志,2016,15(01):34~37

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  • 收稿日期:2015-06-09
  • 最后修改日期:2015-07-24
  • 录用日期:2015-07-24
  • 在线发布日期: 2016-01-25
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