Objective To investigate the differences in the indices of cardiopulmonary exercise testing (CPET) between the elderly and young patients with chronic thromboembolic pulmonary hypertension (CTEPH). Methods Fifty-seven CTEPH patients admitted to the Center for Pulmonary Vascular Diseases, Fuwai Hospital during January 2011 to May 2014 were enrolled in this study. They all underwent CPET, and were divided into 2 groups according to their age, that is, the elderly group (≥60 years old, n＝19), and the younger group (＜60 years old, n＝38). Results There was no difference in gender, prevalence of deep venous thrombosis (DVT), pulmonary targeted drug therapy, pulmonary vascular occlusion rate detected by ventilation-perfusion lung scanning, and WHO functional class between the 2 groups. Compared with the younger patients, the elderly CTEPH patients had lower heart rate response during exercise, decreased forced expiratory volume in one second (FEV1) and forced vital capacity (FVC), lower peak minute ventilation (VE peak) and tidal volume (VT peak). While the percentage of oxygen uptake/heart rate (VO2/HR) peak to prediction and physiologic dead space fraction (VD/VT) were significantly increased in the elderly patients, along with decreased PetO2 peak. Conclusion The elderly CTEPH patients have their own characteristics in the parameters of CPET.