Osteoporotic fracture is a critical complication of osteoporosis. Fracture healing plays an important role in the function recovery and quality of life in the osteoporosis patients. Currently, the effect of anti-osteoporosis treatment on fracture healing is controversial. Some researchers believed that the anti-osteoporosis treatment will increase bone mineral density, relieve pain, and promote fracture healing, etc. However, the others argued that the anti-osteoporosis treatment has no effect on fracture healing, or even also might suppress the healing. Therefore, in this review, we focused on the effect of osteoporosis treatments on osteoporotic fracture healing, so as to guide the osteoporotic fracture therapy.