Objective To determine the clinical features of hyperuricemia and the association between hyperuricemia and accompanied disease in elderly male patients. Methods Elderly male hospitalized patients from 2002 to 2004 in Chinese PLA General hospital were retrospectively analyzed, including 225 patients with hyperuricemia and 225 without, and 110 patients accompanied with diabetes in each group. Demographic information and biochemical examination results were collected and the influential factors of hyperuricemia were analyzed. Results The 10.5% eldely male hospitalized patients presented with hyperuricemia. Significantly more patients were complicated with renal dysfunction in hyperuricemic group than in non-hyperuricemic group (27.6% vs 6.2%, c2＝36.47, P＝0.0000). The age, body mass, body mass index, blood pressure, triglyceride, total cholesterol, fasting glucose, blood creatinine, blood urea, creatinine clearance rate and high density lipoprotein cholesterol of hyperuricemic group were also significantly different with non-hyperuricemic group(P＜0.01). In hyperuricemic group, the morbidity rate of coronary heart disease, hypertension, hypertriglyceridemia, renal dysfunction was higher than those in non-hyperuricemic group(P＜0.01). In hyperuricemic group, the serum uric acid level was significantly associated with age, body mass, body mass index, blood pressure, triglyceride, total cholesterol, HbA1c, blood creatinine, blood urea and creatinine clearance rate (P＜0.01). Conclusions The prevalence of hyperuricemia was high in old male person. Less than 10% hyperuricemia patients had gout, but more (4.5 times) hyperuricemia patients complicated with renal dysfunction than those without hyperuricemia. Hyperuricemia often accompanied with obesity, glucose and lipid metabolic dysfunction and hypertension. Hyperuricemia may be a risk factor of hypertension, coronary heart disease, diabetes and hyperlipidemia. We should pay more attention to the patient with hyperuricemia, and try to diagnose and treat the disorder as early as possible.