Abstract:Heart failure is the serious stage in the process of cardiovascular diseases. Immune activation and cytokines regulate cardiovascular system and play important roles in the pathophysiological process of heart failure. There is a close relationship between levels of circulatory cytokines and cardiac function, prognosis and risk stratification of heart failure. The treatment of immune activation also shows significant therapeutic potential. In this paper, we summarize the relationship of cytokines and heart failure.