老年男性骨量减少的相关因素初探
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Correlated factors for osteopenia in elderly males
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    摘要:

    目的 通过定量超声测定法(QUS)测得骨密度T值, 同时调查各种危险因素, 探讨与老年男性骨质疏松相关的危险因素。方法 老年科体检的60岁以上男性217例, 采用QUS对其进行骨密度的测定, 根据检测结果将其分为骨量正常组、骨量低下组和骨质疏松组, 并对所有患者进行问卷调查, 包括年龄、饮茶、吸烟、体重、血脂、疾病史、用药史等以及血糖、血脂、肌酐清除率等生化指标测定, 比较各因素和骨密度T值之间的关系。结果 年龄、饮茶、高血压、甘油三酯、低密度脂蛋白胆固醇与骨密度呈相关关系(P值分别为0.007, 0.027, 0.049, 0.027, 0.033); 进一步的多因素分析显示, 饮茶与高血压和老年男性骨量减少呈独立相关(P = 0.027, P = 0.088)。结论 饮茶对骨密度呈显著正相关, 高血压等心血管疾病危险因素和老年男性骨量减少存在相关性, 考虑到后一类人群发生骨密度降低的风险, 应定期进行骨密度测定。

    Abstract:

    Objective To investigate the risk factors of osteopenia in the elderly males. Methods Bone mineral density was investigated by Quantitative ultrasound (QUS) in 217 males aged above 60 years who received routine physical examination in outpatient department. These subjects were divided into normal bone mass group, osteopenia group and osteoporosis group according to bone mineral density. All subjects answered the questionnaire, which contained the information on age, tea drinking, smoking, body mass, previous disease history, and medication history. Additionally, blood glucose, blood lipids and creatinine clearance rate were also measured. The correlationship between these factors and bone mineral density were investigated. Results Age, tea-drinking, hypertension, low density lipoprotein cholesterol and triglyceride level were correlated with bone mineral density(P= 0.007, 0.027, 0.049, 0.027 and 0.033 respectively). Tea-drinking and hypertension were independently correlated with bone mineral density (P = 0.027 and 0.088 respectively). Conclusion Tea-drinking is significantly correlated positively with bone mineral density. Some cardiovascular risk factors have correlation with osteopenia in elderly males. It is strongly recommended that these patients should timely undergo bone mineral density measurement.

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王 静, 陆金华, 金 贤, 等.老年男性骨量减少的相关因素初探[J].中华老年多器官疾病杂志,2011,10(5):401~404

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