Objective To investigate the influence of intensive intervention on cadiovascular disease(CVD) in community-dwelling elderly with hypertension or complicated by abnormal lipid metabolism.Methods A cluster sample of 1 215 subjects from 2 different communities in Nanning city were randomly categorized into intensive intervention group and control group.The intensive intervention group received different treatment regimens according to the corresponding disorders,and the control group kept normal medical situation,including seeking medical advice and taking medicine voluntarily.After 43.5 months follow-up,CVD occurrence were recorded.Results After 43.5 months follow-up,the systolic and diastolic blood pressure decreased significantly in both intensive intervention group and control group(P<0.01).There were a total of 40 cases(4.0%) who developed CVD in both groups,among them,there were more patients with hypertension than without hypertension(6.9% vs 2.9%,(χ2=9.004,P=0.003,OR = 2.492,95%CI 1.349-4.601).There were less patients who developed CVD in intensive intervention group than in control group(χ2=4.729 and 6.822,P=0.03 and 0.009,OR=2.645 and 3.438,95%CI 1.006-6.562 and 1.296-9.118).Conclusion Hypertension is a high-risk factor in community-dwelling elderly;both the routine and intensive intervention can significantly decrease the blood pressure of the cases of hypertension or those complicated by abnormal lipid metabolism.Compared with the non-intensive intervention,the intensive intervention can more effectively reduce the occurrence of CVD in community-dwelling elderly.