老年人腹部手术后心衰临床危险因素分析
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Clinical risk factors of heart failure after abdominal operation in elderly patients
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    摘要:

    目的评价老年人腹部手术后发生心衰的相关临床因素。方法选择以腹部手术住院的年龄≥65岁的病例762例,分为心衰组和对照组,其中心衰组32例,占4.2%。回顾性地分析其临床资料并评价发生心衰的相关临床因素。结果心衰发生在术后1~3d19例(59.3%),心衰组高龄患者多于对照组(53.1%vs25.2%);有冠心病和心功能不全病史者较对照组多(分别为62.5%vs38.6%和25.0%vs4.0%);急诊手术发生心衰多于对照组(41.4%vs15.8%);心衰组术前ST段压低≥0.05mV者较对照组多(34.4%vs18.2%)、术后1~3d外周血白细胞>10×109/L者较对照组多(31.3%vs16.0%)、补液量≥2500ml/d者较对照组多(21.9%vs7.1%),差异均有统计学意义。将单因素分析有统计学差异的指标进行多因素logistic分析显示:心功能不全病史(OR=9.52)、急诊手术(OR=15.723)、高龄(OR=2.933)是老年腹部手术患者发生术后心衰的独立预测因素。结论老年人腹部手术后发生心衰患者中高龄、有冠心病史、心功能不全史、急诊手术、术前ST段压低≥0.05mV、术后1~3d外周血白细胞>10×109/L、补液量≥2500ml/d者的比率均高于对照组;老年腹部手术患者发生术后心衰的独立预测因素包括心功能不全病史、急诊手术及高龄。

    Abstract:

    ObjectiveTo evaluate the clinical risk factors of heart failure following an abdominal operation in elderly patients. MethodsA total of 762 patients (≥65 years) who underwent an abdominal operation were divided into heart failure group (n=32) and control group (n=730). Their clinical data were analyzed retrospectively to evaluate the risk factors of heart failure. ResultsNineteen patients (59.3%) sufferred from heart failure at 1-3 days after abdominal operation. Compared with control group,in heart failure group,there were more patients of advanced age(53.1% vs 25.2%),more patients with history of coronary heart disease (62.5% vs 38.6%) and heart failure (25.0% vs 4.0%),more patients following emergency operation(41.4% vs 15.8%),more patients with preoperative ST segment depression (≥0.05mV)(34.4% vs 18.2%),more patients with WBC>10×109/L at 1-3 days after operation(31.3% vs 16.0%),and more patients with infusion fluid ≥2 500ml/d(21.9% vs 7.1%,P<0.05). A multivariable logistic regression analysis showed that the history of heart failure(OR=9.52),emergency operation (OR=15.723) and advanced age (OR=2.933) were independent risk factors of heart failure in elderly patients who underwent an abdominal operation. ConclusionAdvanced age,history of coronary heart disease and heart failure,emergency operation,preoperative ST segment depression,WBC>10×109/L at 1-3 days postoperatively and infusion fluid ≥2 500ml/d are more common in patients with heart failure than patients without heart failure following an abdominal operation. The history of heart failure,emergency operation and advanced age are independent risk factors of heart failure in elderly patients who underwent an abdominal operation.

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林延明,朱慧楠,刘小鹏,许庆,郑曦,富大鹏,康宁超.老年人腹部手术后心衰临床危险因素分析[J].中华老年多器官疾病杂志,2010,9(4):307~311

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