ObjectiveTo evaluate the impact of successful revascularization for chronic total occlusion (CTO) by percutaneous coronary intervention ( PCI) on heart function of heart dysfunction patients. MethodsBetween June 1993 and December 2007,the clinical data of 472 consecutive patients with heart dysfunction undergoing PCI for CTO in the General Hospital of Shenyang Military Command were analyzed.The mean age was (59.4 ±11.5) years. The patients were divided into CTO success group (n=421) and CTO failure group (n=51) respectively according to the results of CTO revascularization by PCI. Six months after CTO revascularization by PCI,the patients underwent cardiac ultrasound examination to compare the heart function between the two groups. ResultsCardiac ultrasound examination was successfully performed in 391 patients (92.9%) in CTO success group and 46 patients ( 90.2%) in CTO failure group at a mean of (6.2±1.7) months after PCI procedures. In CTO success group,left ventricular ejection fraction (LVEF) was significantly increased after PCI procedures 〔(50±6)% vs (44±3)%,P<0.05〕,and left ventricular end-diastolic volume index (LVEDVI) was significantly declined 〔(78±14)ml/m2 vs (85±14)ml/m2,P<0.05〕. But the LVEF and LVEDVI showed no significent change in CTO failure group 〔(42±4)% vs (44±4)%,(87±14)ml/m2 vs (6±15)ml/m2 respectively,P>0.05〕. In addition,compared with CTO failure group,most patients in CTO success group improved in NYHA stage (P<0.05). ConclusionSuccessful CTO revascularization leads to the improvement of left ventricular function in heart dysfunction patients.