老年冠心病患者高尿酸血症与其他危险因素相关性分析
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Correlation between hyperuricemia and other risk factors of coronary heart disease in the elderly
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    摘要:

    目的探讨老年冠心病高尿酸血症(HUA)与其他危险因素的相关性。方法收集2007—2009年在北京大学人民医院住院的300例老年冠心病患者,检测血尿酸(UA)、空腹血糖(FPG)、血压及血脂等指标,并记录年龄、性别、吸烟史、体重指数(BMI),分析HUA与冠心病其他危险因素的相关性。结果 300例冠心病患者中HUA的192例,尿酸正常的108例。Logistic多元回归结果表明,血尿酸与年龄、性别、血压及血脂水平、BMI均具有正相关性。HUA组冠心病患者的血压、血脂水平、BMI均明显高于尿酸正常组的冠心病患者。结论冠心病患者合并HUA的发病率高,后者常常与血压、血脂、血糖代谢异常并存,是冠心病的危险因素之一。

    Abstract:

    Objective To study the correlation between hyperuricemia (HUA) and other risk factors of coronary heart disease (CHD) in the elderly. Methods Totally 300 elderly CHD patients hospitalized from 2007 to 2009 in People’s Hospital,Peking University,were selected. Serum levels of uric acid,fasting blood glucose (FBG),blood pressure,total cholesterol,high density lipoprotein-cholesterol,low density lipoprotein-cholesterol and triglycerides were detected. The subjects’ age,sex,smoking history and body mass index (BMI) were also recorded. The correlation between HUA and other risk factors of CHD were analyzed. Results Among 300 CHD cases,HUA was confirmed in 192 cases,and 108 cases had normal uric acid levels. Logistic analysis showed that the level of serum uric acid was positively correlated with age,sex,blood pressure,serum lipid and BMI. The blood pressure,serum lipid levels and BMI were significantly higher in patients with HUA than in patients with normal uric acid level. Conclusion There is a high prevalence of HUA in CHD patients. HUA frequently co-exists with the disorders of blood pressure,disturbance of serum lipid and glucose metabolism. HUA is one of the risk factors for CHD.

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TONG XiaoMei GUO DanJie.老年冠心病患者高尿酸血症与其他危险因素相关性分析[J].中华老年多器官疾病杂志,2010,9(3):261~263+267

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