老年代谢综合征患者药物治疗情况分析
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全军医药卫生科研基金(糖尿病与代谢综合征的综合防治,07BJZ03)


Analysis of rationality of pharmacotherapy for elderly patients with metabolism syndrome
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    摘要:

    目的分析近年来老年代谢综合征患者药物治疗的有效性、达标率及相关费用。方法采用回顾性病历调查方式对2008-2009年在我科住院符合代谢综合征(中华医学会糖尿病分会)标准的老年病例进行分析(n=206),记录代谢综合征相关各组分治疗用药、疗效、费用和控制达标情况。结果经过近年来对代谢综合征治疗的关注,本组老年代谢综合征患者降血糖、降血压、调血脂、降尿酸、抗凝血的药物治疗率分别达到98.0%,70.9%,85.0%,42.6%,83.3%。糖化血红蛋白、空腹血糖、餐后血糖、血压、甘油三酯、高密度脂蛋白及血尿酸控制达标率分别为45.1%,70.0%,52.9%,79.1%,74.6%,80.2%,40.0%;达到良好控制的分别为85.0%,88.9%,93.7%,99.4%,95.6%,77.5%,97.0%。上述各项用药总体日均费用<30元、30~60元和60元以上分别占50.0%,38.3%,11.7%。结论掌握老年代谢综合征患者的特点及综合治疗原则,合理选择各种药物,可以使代谢综合征患者在各项控制指标达标的同时获得较高的效价比。?更多还原

    Abstract:

    Objective To discuss the efficacy,qualification rate and costs of pharmacotherapy for elderly patients with metabolism syndrome.Methods The investigation was based on a descriptive analysis related to medical files of 206 elderly in-patients (>60-year-old) with metabolism syndrome (MS) during 2008 to 2009.The diagnosis was confirmed by the standards of Chinese Diabetes Association.The agents used for each component of MS,therapeutic effect,costs,and qualification rate were recorded.Results The efficiency rates of the pharmacotherapy for diabetes,hypertension,hyperlipidemia,hyperuricemia and anticoagulation were 98.0%,70.9%,85.0%,42.6% and 83.3% respectively.The qualification rates of control of HbA1c,fasting glucose,postprandial glucose,blood pressure,triglyceride,HDL,and uricemia were 45.1%,70.0%,52.9%,79.1%,80.2% and 40.0% respectively.The more satisfaction rates of control of these indices were 85.0%,88.9%,93.7%,99.4%,95.6%,77.5% and 97.0% respectively.The daily costs of all the agents used for metabolism syndrome <30 yuan,30-60 yuan,and >60 yuan accounted for 50.0%,38.3% and 11.7% respectively.Conclusion In order to get satisfactory qualification rate,as well as ideal cost-effectiveness ratio,the medications should be chosen reasonably according to the characteristics of elderly patients with metabolism syndrome and the principles of comprehensive therapy.

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孙般若 肖海英 成晓玲 李志冰 田慧.老年代谢综合征患者药物治疗情况分析[J].中华老年多器官疾病杂志,2010,9(2):118~122

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