老年冠心病合并心房颤动患者轻度认知功能障碍与运动能力的相关性研究
CSTR:
作者:
作者单位:

(新疆医科大学第一附属医院心力衰竭科,乌鲁木齐 830000)

作者简介:

通讯作者:

中图分类号:

基金项目:

新疆维吾尔自治区自然科学基金(2022D01E70)


Correlation between mild cognitive impairment and motor ability in elderly patients with coronary heart disease complicated with atrial fibrillation
Author:
Affiliation:

(Heart Failure Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China)

Fund Project:

This iwork was supported by NaturalScienceF "Xinjian ygur Autonomous Region(2022DO1E70)

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 研究老年冠心病(CHD)合并心房颤动(AF)患者轻度认知功能障碍(MCI)与运动能力的相关性。方法 选取2024年1月至2025年1月新疆医科大学第一附属医院收治的116例老年CHD合并AF患者作为研究对象,采用简易精神状态评估(MMSE)量表及蒙特利尔认知评估(MoCA)量表评估患者认知功能,根据评估结果将患者分为MCI组和对照组,对所有患者进行握力、步行速度及计时起立-行走测试,评估并比较MCI组与对照组患者肌肉量、移动能力及动态平衡能力。采用SPSS 27.0软件进行数据分析,根据数据类型,组间比较分别采用t检验或χ2检验。采用二元logistic回归模型分析影响老年CHD合并AF者MCI发生的相关因素,绘制受试者工作特征(ROC)曲线,分析logistic回归模型在预测患者MCI中的价值。结果 116例老年CHD合并AF患者中有110例(94.83%)完成本次研究,其中33例检出MCI,检出率为30.00%。MCI组患者计时起立-行走测试耗费时间长于对照组,步行速度及握力水平低于对照组,差异均有统计学意义(均P<0.05)。以老年CHD合并AF患者是否发生MCI作为因变量,行logistic回归分析结果显示,年龄(70~80岁)(OR=3.766,95%CI 1.709~8.297; P=0.001)、糖尿病(OR=1.943, 95%CI 1.295~2.915; P=0.001)、吸烟史(OR=1.418, 95%CI 1.202~1.671; P<0.001)、高尿酸血症(OR=1.508, 95%CI 1.009~2.254; P=0.046)、Gensini评分≥64分(OR=1.721, 95%CI 1.246~2.378; P=0.001)及计时起立-行走测试结果(OR=2.115, 95%CI 1.399~3.198; P<0.001)是其危险因素,大专及以上学历(OR=0.621, 95%CI 0.479~0.806; P<0.001)是其保护因素。ROC曲线结果显示,预测模型的ROC曲线下面积为0.919(95%CI 0.850~0.988),Hosmer-Lemeshow拟合优度检验结果提示模型可靠度较好。结论 老年CHD并AF者MCI发生率较高,发生MCI者运动能力下降,年龄、受教育程度、糖尿病、吸烟史、高尿酸血症、Gensini评分及计时起立-行走测试结果是MCI发生的影响因素,以此构建的预测模型在预测老年CHD合并AF患者MCI发生风险中的价值良好。

    Abstract:

    Objective To investigate the correlation between mild cognitive impairment (MCI) and motor ability in elderly patients with coronary heart disease (CHD) and atrial fibrillation (AF). Methods A total of 116 elderly patients with CHD and AF admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2024 to January 2025 were enrolled. Cognitive function was assessed using the mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA). Patients were divided into a MCI group and a control group according to the assessment results. All patients underwent grip strength, walking speed, and timed up-and-go (TUG) tests to evaluate and compare muscle mass, mobility, and dynamic balance ability between the MCI group and the control group. SPSS 27.0 was used for data analysis. According to data type, independent samples t test or Chi-square test was used for comparison between two groups. Binary logistic regression model was used to analyze the factors associated with MCI in elderly patients with CHD and AF, and receiver operating characteristic (ROC) curves were plotted to analyze the value of the logistic regression model in predicting MCI. Results Of the 116 elderly patients with CHD and AF, 110 (94.83%) completed the study, among whom 33 were diagnosed with MCI, with a detection rate of 30.00%. Patients in the MCI group had a longer TUG time, and lower walking speed and grip strength than the control group, with statistically significant differences (all P<0.05). Using the occurrence of MCI in elderly patients with CHD and AF as the dependent variable, logistic regression analysis showed that age (70-80 years) (OR=3.766,95%CI 1.709-8.297; P=0.001), diabetes mellitus (OR=1.943,95%CI 1.295-2.915; P=0.001), smoking history (OR=1.418,95%CI 1.202-1.671; P<0.001), hyperuricemia (OR=1.508,95%CI 1.009-2.254; P=0.046), Gensini score≥64 points (OR=1.721,95%CI 1.246-2.378; P=0.001), and TUG test results (OR=2.115,95%CI 1.399-3.198; P<0.001) were risk factors, while junior college education or above (OR=0.621,95%CI 0.479-0.806; P<0.001) was a protective factor. ROC curve analysis showed an area under curve of 0.919 (95%CI 0.850-0.988) for the prediction model, and the Hosmer-Lemeshow goodness-of-fit test indicated good reliability of the model. Conclusion The incidence of MCI is high in elderly patients with CHD and AF, and those with MCI have decreased motor ability. Age, educational level, diabetes mellitus, smoking history, hyperuricemia, Gensini score, and TUG test results are influencing factors for MCI. The prediction model constructed based on these factors shows good value in predicting MCI in elderly patients with CHD and AF.

    参考文献
    相似文献
    引证文献
引用本文

努尔比亚·麦麦提依明,魏周仙,仉珍.老年冠心病合并心房颤动患者轻度认知功能障碍与运动能力的相关性研究[J].中华老年多器官疾病杂志,2026,25(8):589-594
DOI:10.11915/j. issn.1671-5403.2026.08.118

复制
分享
相关视频

文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2025-08-01
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2026-09-10
  • 出版日期:
文章二维码