【Abstract】Objective To analyze the factors influencing compliance with lifestyle intervention in the elderly patients with newly-diagnosed type 2 diabetes mellitus (T2DM). Methods A retrospective analysis was made of the clinical data of 86 elderly patients with newly-diagnosed T2DM admitted to Haikou Hospital Affiliated to Xiangya School of Medicine, Central South University, from January to June 2022. Their compliance with lifestyle intervention was assessed at follow-up visits 6 months later. The patients were divided into poor compliance group (n=41) and good compliance group (n=45). The two groups were compared in demographic characteristics, homeostasis model assessment-insulin resistance (HOMA-IR) and homeostasis model assessment-islet β cell function index (HOMA-β). SPSS statistics 23.0 was employed to process and analyze the data. According to the data type, t test,χ2 test or continuous correctedχ2 test was used for comparison between groups. Binary logistic regression analysis was used to analyze the factors influencing compliance with lifestyle intervention in the elderly patients with newly-diagnosed T2DM. Results HOMA-IR in both groups at follow-up visits was reduced compared with that at the first visit (P<0.05), and HOMA-IR in the good compliance group was lower than that in the poor compliance group (P<0.05). HOMA-β in both groups was enhanced compared with that at the first visit (P<0.05), and HOMA-β in the good compliance group was higher than that in the poor compliance group (P<0.05). Binary logistic regression analysis showed that divorced/widowed (OR=2.633,95%CI 1.513-4.581; P<0.05), living alone (OR=2.326,95%CI 1.218-4.442; P<0.05), and having a family history of diabetes mellitus (OR=0.655,95%CI 0.197-0.983; P<0.05) were contributing factors of poor compliance with lifestyle intervention in the elderly T2DM patients. Conclusion Among the elderly patients with newly-diagnosed T2DM, those with poor compliance with lifestyle intervention have poor islet β cell function and insulin resistance control, the divorced/widowed and the solitary are more likely to have a poor compliance with lifestyle intervention, and those with a family history of diabetes mellitus often have a good compliance.
