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首页 > 过刊浏览>2022年第21卷第2期 >148-151. DOI:10.11915/j.issn.1671-5403.2022.032
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衰弱老年人中肠道菌群相关研究进展
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(1. 成都中医药大学附属第五人民医院老年医学科,;2. 中国成都-法国蒙彼利埃老年疾病研究所,成都 611130)


Progress in gut microbiota related researches in frail elderly
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(1. Department of Geriatrics, Fifth People′s Hospital of Chengdu Affiliated to Chengdu University of TCM,Chengdu 611130, China ;2. China Chengdu-France Montpellier Institute of Geriatric Diseases, Chengdu 611130, China)

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    【摘要】衰弱是常见的老年综合征,是健康老龄化中面临的严峻课题,但其发病机制并不十分明确。目前一致认为衰弱是由多因素导致,其中免疫功能失调和慢性炎症在衰弱中发挥重要作用。由于肠道菌群与免疫功能及慢性炎症相关,因此近年来肠道菌群与衰弱的相关性也逐渐受到关注。本文主要介绍肠道菌群在老年衰弱中的研究进展,为老年衰弱的发病机制提供依据。

    基金项目:2018年成都中医药大学医院专项课题(YYZX20180021)；成都中医药大学附属第五人民医院资助项目(KYJJ2020-03)

    【Abstract】Frailty, a common geriatric syndrome, is a serious problem in healthy aging. However, its pathogenesis remains unclear. It is a general agreement that frailty is caused by multiple factors, in which immune dysfunction and chronic inflammation play an important role. Because gut microbiota is associated with immune function and chronic inflammation, the correlation between gut microbiota and frailty has drawn increasing attention in recent years. This article mainly introduced the progress in the research of gut microbiota in the frail elderly, providing the reference for the pathogenesis of frailty.

    This work was supported by Special Hospital Project of Chengdu University of TCM in 2018(YYZX20180021) and the Fifth People′sHospital of Chengdu Affiliated to Chengdu University of TCM (KYJJ2020-03).

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管丽娟,郑晓梅,刘茜.衰弱老年人中肠道菌群相关研究进展[J].中华老年多器官疾病杂志,2022,21(2):148-151

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  • 收稿日期:2020-12-20
  • 在线发布日期: 2022-03-03
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主管单位：中国人民解放军总医院
主办单位：解放军总医院医学创新研究部、国家老年疾病临床医学研究中心（解放军总医院）、解放军总医院第六医学中心心血管病医学部
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