(1.保定市第一中医院急诊科,保定 071000;2. 解放军第252医院老年心血管病研究诊疗中心,保定 071000)
R452
(1. Department of Emergency, Baoding NO.1.Hospital of TCM, Baoding 071000, China;2. Department of Cardiology, Geriatric Cardiovascular Disease Research and Treatment Center, No. 25;2.Hospital of PLA, Baoding 071000, China)
【摘要】羟甲基戊二酰辅酶A还原酶抑制剂(通常称为他汀类药物)是最常用的药物种类之一。他汀治疗在心血管疾病的一级和二级预防中可显著降低死亡率及发病率,但一部分患者服用他汀后会发生不良反应,长期使用的不良后果令人担忧。因此,有必要研究他汀类药物不良反应并对其作出有效应对,这有利于提高临床用药安全,增加患者依从性。
基金项目:
【Abstract】Hydroxymethylglutaryl-coenzyme A reductase inhibitors (commonly known as statins) are among the most frequently used drug classes. Although primary and secondary prevention of cardiovascular diseases with statins can significantly reduce mortality and morbidity, adverse reactions occur in some patients taking statins, leading to concern about the negative consequences associated with their long-term use. It is therefore necessary to investigate the adverse reactions of statins with a view of seeking for effective management strategies, which will be conducive to the improved safety and increased patient compliance.
张君实,李月敏,曹雪滨.他汀类药物不良反应评价及有效应对[J].中华老年多器官疾病杂志,2018,17(11):877-880
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