Chronic heart failure (CHF) is a common heart disease, and sarcopenia is a recently recognized disease by the World Health Organization in 2016, characterized by a progressive decrease in skeletal muscle mass, muscle strength, and/or physical performance. Both are highly prevalent in the elderly. This article provides a comprehensive review of the epidemiological features, pathogenesis, interventions, and prognosis of patients with both sarcopenia and CHF. Current evidence suggests that sarcopenia has a high prevalence in CHF patients, but the mechanisms has not been elucidated. However, anorexia, malnutrition, reduced physical activities, chronic inflammation, and changes in hormone levels due to CHF might contribute to the occurrence of sarcopenia. Appropriate amount of exercise and nutritional supplements may be beneficial in patients with comorbid CHF and sarcopenia, and vitamin D supplementation may be beneficial for those with low serum vitamin D. In light of the fact that sarcopenia can shorten survival, increase readmission rates, and decrease quality of life of CHF patients, it is necessary to improve the awareness of CHF patients and clinicians about sarcopenia, and screening, prevention, and intervention should be implemented as early as possible for sarcopenia in CHF patients.