Progress research on pathogenesis and exercise treatment of chronic heart failure in patients complicated with sarcopenia
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(1. College of Rehabilitation Sciences, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China;2. College of Exercise and Health Sciences, TianJin University of Sport, Tianjin 301617, China)

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R541.6

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    Abstract:

    Sarcopenia is a common complication of elderly patients with chronic heart failure and one of the most important risk factors affecting the prognosis of patients. Research studies in recent years indicate that malnutrition, physical inactivity, low muscle blood flow, inflammation, hormonal changes, ubiquitin proteasome system, autophagy, apoptosis and oxidative stress play roles in the pathogenesis of sarcopenia induced by chronic heart failure, and exercise therapy is the effective treatment way. The research progress of these fields was reviewed in this paper, hoping to provide reference experience for clinical medical workers.

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History
  • Received:January 18,2021
  • Revised:
  • Adopted:
  • Online: May 30,2022
  • Published: