(Department of Geriatrics, Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China)
Clc Number:
R339.3+8
Fund Project:
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Abstract:
Cardiac aging and cardiac senescence-associated cardiovascular diseases continue to be a serious problem that increases the social burden. Revealing the molecular mechanisms of cardiac aging and cardiac senescence-associated cardiovascular diseases provides a new opinion for the early diagnosis and treatment of delaying aging and diseases. A microRNA (miRNA) is a small single-stranded non-coding RNA molecule that has been found to be involved in the regulation of gene expression at the post-transcriptional level. This paper focuses on the structure and function of miRNA, and its regulatory effects on the characteristics and molecular mechanisms of aging hearts and on age-related cardiovascular diseases.