Lower extremity arteriosclerosis obliterans (ASO) is one of the most common peripheral vascular diseases. The risk factors for ASO include age, gender, smoking history, hypertension, hyperlipidemia, coronary heart disease, and hyperhomocysteinemia. Although some progresses have been made in current treatments such as surgical procedures, endovascular techniques, and drug therapy, ASO remains a major cause of amputations. Therefore, it is very important to master the related risk factors for ASO and prevent them as early as possible in the elderly patients. Interventional therapy has the advantages of small trauma, easy operation, quick recovery and good reproducibility, and has become the first choice for the treatment of lower extremity ASO.