Therapeutic value of curcumin for Alzheimer’s disease and methods to increase its bioavailability
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Key words:curcumin  Alzheimer’s disease  treatment
Author NameAffiliationE-mail
YU Xiao-Wen1, WANG Xiao-Qing2, ZHANG Wen-Jun1, WANG Shi-Bo1, YANG Ling1, WANG Yue1, TUO Xi-Ping1* 1Department of Geriatrics, 2Department of Neurology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China 
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      Alzheimer’s disease (AD), as the main cause of senile dementia, has become a serious threat to human health. Epidemiological evidence shows that curcumin is of g)reat effectiveness for AD, and it attracts much attention because of its great safety since it is derived from human food source. This article reviewed the therapeutic value of curcumin for AD based on the pathological changes of AD after curcumin treatment, the pharmacokinetics of curcumin and methods to increase its bioavailability.