Clinical features of eosinophilic granulomatosis with polyangiitis in the elderly
  
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DOI:10.11915/j.issn.1671-5403.2015.12.217
Key words:eosinophilic granulomatosis with polyangiitis  aged
Author NameAffiliationE-mail
WANG Wen-Yue1, YU Chang-Li1, SHI Ju-Hong2* 1Department of Respiratory Diseases, North China University of Science and Technology, Tangshan 063000, China
2Department of Respiratory Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China 
shijh@pumch.cn 
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Abstract:
      Eosinophilic granulomatosis with polyangiitis (EGPA) is mainly characterized by eosinophil-rich and necrotizing granulomatous inflammation and necrotizing vasculitis, predominantly affecting small to medium vessels, often involving the respiratory tract (asthma). Its radiological manifestations are non-persistent patchy migratory pulmonary infiltrates, ground-glass opacities, consolidation, nodules, pleural effusion, and may be interstitial lung changes. EGPA is common in adults, without obvious sex predominance. Age is one of poor prognostic factors, and the aged patients tend more frequently to have complications and a higher mortality. In this article, we reviewed the literatures concerning EGPA in the elderly and summarized its clinical characteristics.
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