Chronic obstructive pulmonary disease (COPD), characterized by high prevalence, high morbidity and mortality, mainly involves the lungs, but also causes systemic adverse reactions, and osteoporosis is one of the common extra-pulmonary manifestation. In recent years, the prevalence of COPD combined with osteoporosis is increased significantly, and osteoporosis becomes one of the important factors of disability and death in COPD patients. In order to explore the relationship between the COPD and osteoporosis, in this paper, we focused on the new progress in the research of COPD-related aspects of osteoporosis so as to have a comprehensive understanding of its inducing factors, prevention and treatment.