Correlation of heart valvular diseases with pulmonary hypertension:a clinical analysis
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    Abstract:

    Objective To investigate the relative features of heart valvular diseases (HVD) and pulmonary hypertension (PH), and the risk factors of PH by analyzing the clinical data of these patients. Methods A total of 256 HVD patients with complete clinical data receiving surgical treatment in our hospital from April 2010 to October 2011 were subjected in the study. A retrospective analysis was carried out on case history, signs and symptoms, results of echocardiography and others on. The patients were divided into non-PH group (n=157, pulmonary pressure<35mmHg; 1mmHg=0.133kPa), suspected PH group (n=50, pulmonary pressure 35 to 50mmHg) and PH group (n=49, pulmonary pressure>50mmHg). Different statistical methods including multiple regressive analysis were used between these HVD patients with PH and without PH. Results In all of the 256 HVD patients, 49 patients were diagnosed with PH according to the diagnostic criteria of the European Society of Cardiology 2009. The HVD patients complicated with PH had an average age of 50.2 years, in a ratio of male to female of 18∶31. The Heart function grade of New York Heart Association (NYHA; OR=1.243), left atrial diameter (LAD; OR=1.016) and the duration of heart failure (OR=1.018) were the risk factors of PH in HVD patients. Conclusion HVD is an important cause of PH. Significant differences are seen between PH patients and non-PH patients in body mass index, NYHA grade, LAD, duration of heart failure and atrial fibrillation. The lower heart function grade of NYHA, the larger LAD, and the longer duration of heart failure are risk factors for PH.

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  • Online: January 02,2014
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