Objective To evaluate the impact of the myocardial reperfusion status after percutaneous coronary intervention(PCI) on improvement of left ventricular function in acute myocardial infarction patients by intracoronary myocardial contrast echocardiography(MCE).Methods Eighteen acute myocardial infarction patients were selected and injected with SonoVue via left main or right coronary artery before and 15 minutes after PCI respectively.MCE images were visually valued with score on the perfusion situation of segmental myocardial regions.Left ventricular function in all patients was evaluated at 1 month after PCI.The perfusion score index(PSI) and wall motion score index(WMSI) were calculated by definite formulae.Results Among 30 myocardial segments with PSI as 0 before PCI,there were 20(66.7%) had the WMSI of 3-5 at 1 month after PCI.Among 11 myocardial segments with PSI as 2 before PCI,there were 8(72.7%) had the WMSI of 1-2 at 1 month after PCI.Statistical analysis showed that the level of myocardial reperfusion before PCI was related to the postoperative 1-month status of left ventricular segmental wall motion(P<0.05).Among 12 myocardial segments with PSI as 0 after PCI,there were 11(91.7%) had the WMSI of 3-5 at 1 month after PCI.Among 22 myocardial segments with PSI as 2 after PCI,there were 17(77.2%) had the WMSI of 1-2 at 1 month after PCI.Statistical analysis showed that the level of myocardial reperfusion after PCI was also related to the 1-month status of left ventricular segmental wall motion(P<0.01),and was obviously associated with left ventricular systolic function at 1 month after PCI(P<0.01).Conclusion The myocardial reperfusion status affects the improvement of left ventricular function after PCI in AMI patients.Intracoronary MCE can estimate the level of myocardial perfusion and left ventricular function.It might have the predictive value on clinical prognosis.