Objective To investigate the relationship between ambulatory blood pressure (ABP) and renal dysfunction in patients aged ≥70 years with cardiovascular diseases(CVD). Methods Eighty-four patients aged 70-87 years with CVD were included. The glomerular filtration rate (GFR) was estimated with the simplified Modification of Diet in Renal Disease study (MDRD) equation,and GER <60 ml/(min·1.73 m2) was considered as renal dysfunction. The patients were divided into renal dysfunction group (n=44) and control group with normal renal function (n=40). The 24-hour ABP parameters were compared between two groups. Results There were more patients with coronary artery disease,diabetes,heart failure or mean systolic blood pressure(SBP) >130 mmHg in renal dysfunction group than in control group. There was no significant difference in numbers of hypertension cases and non-dipper blood pressure cases. The mean pulse pressure (PP) was significantly higher,while maximal diastolic blood pressure (DBPmax) and wave amplitude of DBP (ΔDBP) were lower in renal dysfunction group than in control group. Mean SBP,PP,nocturnal SBP (nSBP) and nSBP load were positively correlated with the patients age. Serum creatinine(SCr) was positively correlated with PP,nSBP and minimum SBP (SBPmin),and negatively correlated with DBPmax and ΔDBP. GFR changed correspondingly. The correlation of SCr with PP and nSBP remained significant after age-matching. Conclusion The increase in PP and nSBP and the decline in DBPmax and ΔDBP are correlated with renal dysfunction in aged patients with CVD. Patients with renal dysfunction are more vulnerable to suffer from coronary artery disease,diabetes,and heart failure. They also displayed more remarkable changes of ABP.