Objective To investigate the clinical characteristics of complete left bundle branch block (CLBBB) patients complicated by coronary heart disease (CHD). Methods The data of 733 hospitilized patients (from January 2002 to January 2008) with CCLBBB were retrospectively analyzed. The difference in clinical characteristics between CCLBBB patients complicated with and without CHD were compared. The independent predictors for CHD in CCLBBB patients were determined by regression analysis. Results The CLBBB patients complicated by hypertension,CHD and dilated cardiomyopathy accounted for 49.4%,44.1% and 26.5%,respectively. About 58% of CLBBB patients were complicated with cardiac dilation or myocardial dysfunction,and 19.9% with other arrhythmia. The results of logistic analysis showed that sex (P<0.001,B=1.991,95%CI:1.375-2.882),age ≥65 years(P<0.001,B=2.793,95%CI:1.948-4.005),hypertension(P=0.022,B=1.522,95%CI:1.062-1.640),diabetes mellitus (P<0.001,B=2.459,95%CI:1.540~3.926),hyperlipemia(P=0.803,B=1.057,95%CI:0.682-2.180)were positively related to CHD; dilated cardiomyopathy (P<0.001,B=0.072,95%CI:0.045-0.127),rheumatic valvular disease (P=0.027,B=0.253,95%CI:0.075-0.853),and atrial fibrillation or atrial flutter (P=0.024,B=0.564,95%CI:0.343-0.927) and other atrio-ventricular block(P<0.001,B=0.418,95%CI:0.263-0.665) were negatively related to CHD. Conclusion CLBBB patients,≥65 years,male sex,with hypertension or diabetes mellitus,are more susceptibly to suffer from CHD. While dilated cardiomyopathy,atrial fibrillation or atrial flutter,other atrio-ventricular block,cardiac dilation or myocardial dysfunction are more common in CLBBB patients without CHD.