Objective To explore the clinical features of sinus heart rate turbulence (HRT) in patients with chronic congestive heart failure (CHF) and its relationship with heart function,and to discuss its prognostic significance. Methods One hundred patients (61 males and 39 females;age 45-86 years,mean 62 years) with CHF and 50 controls without structural heart diseases were enrolled. All subjects underwent 24-h Holter electrocardiogram (ECG) recordings,cardiac echocardiography,and 12-lead ECG. Two HRT parameters,turbulence onset (TO) and turbulence slope (TS) were calculated. Left ventricle interior diameter and ejection fraction (LVEF) were determined. Results TO was significantly different between CHF group and control group(0.4839±0.1421)% vs-(0.3467±0.1352)%,P<0.01,so was TS(2.1638±0.2547)ms/RR interval vs (6.2434±1.3589)ms/RR interval,P<0.01. During a follow-up of 0.5 to 2 years,both the mortality and the rehospitalization rate were higher in patients with abnormal TS and/or TO than in patients with normal TO and TS. Conclusion HRT reflects the baroreflex sensitivity and autonomic nervous system function,which has prognostic significance in CHF patients.?更多