Abstract:目的分析老年冠心病（CAD）介入治疗的安全性和其影响因素。方法回顾性对比分析连续1754例CAD病人的主要临床和介入资料特点。根据年龄将病例分为成人组（≤64岁）526例、老年组（65～74岁）765例、高龄组（75～84岁）293例，超高龄组（≥85岁）170例。结果老年组与成人组、老年各亚组之间、高龄高危复杂病例组（679例，占55．3％）与老年组之间在介入操作成功率、并发症、围术期病死率和随访主要心脏不良事件发生率方面均无显著差异（P〉0．05）。结论（1）对老年CAD病人施行介入治疗操作安全可行。（2）与普通成人相比，对高龄、高危和复杂CAD病人施行介入治疗并不增加并发症和病死率。（3）操作条件和技术水平是影响老年CAD介入治疗质量的重要因素。

Abstract:Objective To study the efficacy and safety of fructose-1,6-diphosphate (FDP) in treatment of acute cerebral infarction. Methods A multicenter, randomized, double-blind, placebo-controlled study was carried out. The patients with acute cerebral infarction

Abstract:目的探讨盐敏感性高血压病患者血浆血栓素B2(TXB2)、6-酮-前列腺素F1α(6-k-PG-F1α)水平的变化及意义.方法 采用改良的Sullivan急性口服盐水负荷试验的方法将60例高血压病患者分为盐敏感性(SS,28例)和非盐敏感性(NSS,32例)两组.30例正常人为对照组.采用放射免疫法测定其血浆TXB2和6-k-PGF1α水平.结果SS高血压病组血浆TXB2水平[(48.76±21.34)pg/ml]显著高于NSS高血压病组[(31.67±5.30)pg/ml]及正常组[(30.01±7.72)pg/ml](P均＜0.01);SS高血压病组血浆6-k-PGF1α水平[(62.67±17.14)pg/ml]明显低于NSS高血压病组[(92.70±33.72)pg/ml]及正常组[(93.40±20.40)pg/ml](P均＜0.01);NSS高血压病组与正常组间血浆TXB2和6-k-PGF1α水平均无显著性差异(P均＞0.05).结论SS高血压病患者存在血管内皮功能受损和血小板活性增强.

Abstract:目的探讨恶性肿瘤并发下肢深静脉血栓形成(DVT)的发病时间和原因.方法 回顾性分析44例恶性肿瘤并发DVT的恶性肿瘤部位,手术与DVT发病的时间以及诊治方法等.结果经统计恶性肿瘤并发下肢DVT者,可发生在肿瘤根治术后的任何时间或非手术者中,非手术患者占41%(18/44).发生于术后6个月以内的手术患者中,多数发生于术后1～3个月内(9/14,占64%),发生于1周之内者较少(2/14).术后1年以上并发DVT者,大多同时发现有肿瘤转移病灶.经各类药物治疗,肢体肿胀均有明显消退.DVT的发生绝大多数与肿瘤局部压迫无关.结论对DVT患者应高度警惕有否恶性肿瘤发生,如有相关症状,应作相应肿瘤检查,以便尽早治疗.恶性肿瘤行根治术后1～3个月是并发DVT的高峰期,恶性肿瘤多年后并发DVT,常提示可能有肿瘤转移发生.

Abstract:Objective To study the efficacy of ultrasound-guided drainage and urokinase injection to the pleural cavity in treatment of multilocular encircled pleural effusion. Methods Seventy-six patients with multilocular encircled pleural effusion were randomly di

Abstract:Objective To investigate the change of the level of T-lymphocyte subsets (CD_4,CD_8), complements(C_3,C_4) and immunoglobulins (IgA,IgG,IgM) in the COPD patients receiving long-term mechanical ventilation. Methods Forty-two COPD patients receiving long-te

Abstract:Objective To study diabetic foot ulceration and its risk factors in diabetic patients. Methods Case analysis study was carried out to assess the general clinical data, and foot conditions related to diabetic foot ulceration in 530 patients with diabetes m

Abstract:目的研究别隐品碱(ALL)抗心律失常效应及其对心室肌动作电位的影响.方法 选择大鼠和豚鼠以静脉给乌头碱、哇巴因和氯化钡造动物心律失常的模型,观察ALL对心律失常的效应,分离豚鼠乳头状肌观察ALL对动作电位的影响.结果ALL(30和100mg/kg)对乌头碱、哇巴因和氯化钡致动物实验性心律失常有良好的对抗作用,使各种试剂诱发的室早、室速、室颤及停搏的剂量增加.ALL可降低动作电位上升幅度(APA)和0相最大上升速率(Vmax).3.0～100.0 μmol/L的ALL以浓度依赖性方式使离体乳头状肌动作单位时程(APD)延长,其中30.0μmol/L的ALL使APD90延长67.5%.结论ALL具有抗实验性心律失常的效应,此效应可能与其影响心肌组织的电生理密切相关.

Abstract:Objective To detect the aging-related changes in electrophysiologic properties of pulmonary myocardial sleeves in dogs and to seek the experimental evidence for primary or independent factor contributing to atrial fibrillation(AF) incidence. Methods Two 4

Abstract:Objective To examine the expression of estrogen receptor(ER) in different hormone-producing pituitary tumors in order to study the relationship between the specific hormone-secreting adenoma cells and the ER-immunoreactive tumorous pituitary cells. Method