Objective To investigate the effect of Kidney-Tonifying and Blood-Activating decoction combined with neuromuscular joint facilitation (NJF) techniques on prognosis of elderly patients with stroke accompanied by flaccid-paralysis dysfunction. Methods A total of 112 elderly stroke patients with flaccid paralysis admitted in our hospital from February 2021 to January 2023 were recruited, and randomly divided into control group (n=56) and observation group (n=56). The control group was given NJF techniques for rehabilitation, and the observation group was given a traditional Chinese medical prescription (Kidney-Tonifying and Blood-Activating decoction) on the basis of the treatment of the control group. The clinical efficacy was compared between two groups, in terms of the pre- and post-treatment changes in maximum flexion angle and maximum extension angle of the hip and knee joints, surface electromyography (EMG) signals of gastrocnemius and anterior tibia muscle, and hemorheological indicators [such as high- and low-shear whole blood viscosity (WBV), plasma viscosity (PV), hematocrit (HCT)], as well as scores of Fugl-Meyer Assessment (FMA) for Lower Limb Motor Function and Barthel index for activity of daily life (ADL-Barthel). SPSS statistics 20.0 was used for statistical analysis. Data comparison between two groups was perfomed using t test or χ² test depending on data type. Results The effective rate of treatment was significantly higher in the observation group than the control group (67.86% vs 48.21%, P<0.05), but there was no statistical difference in the efficiency between them. In six weeks and two months after treatment, the high-shear WBV value, low-shear WBV value, PV value and HCT level were decreased in both groups when compared with the levels before treatment, with those in the observation group more significant. At the same time points, the maximum flexion and extension angles of the hip and knee joints were increased than before treatment, and the observation group obtained better results than the control group. Similar results were observed in the root mean square (RMS) and integrated electromyography (IEMG) of the gastrocnemius muscle and the tibialis anterior muscle, and in FMA score and ADL-Barthel index in the two groups when compared with before treatment and between two groups (P<0.05). What′s more, better results were obtained in above indicators in both group when compared the levels in two months than those in six weeks after treatment (P<0.05). Conclusion Kidney-Tonifying and Blood-Activating decoction combined with NJF techniques can result in better improvement in hemorheological and motor function and promote the recovery of activity of daily life in senile stroke patients with flaccid paralysis.