Chronic kidney disease (CKD) is an important health problem in the elderly, whose prognosis is affected by multiple factors. Frailty is an important geriatric syndrome prevalent in patients with CKD. Frailty is associated with an increased risk for all-cause death and cardiovascular disease, acute kidney injury and CKD progression. Frailty is a significant predictor of adverse health outcomes, and its early detection and timely interventions are of great significance in improving the prognosis of the elderly CKD patients.