Intensive glucose control can reduce the risk of microvascular and macrovascular complications in the patients with early type 2 diabetes mellitus (T2DM). However, elderly patients are characterized by being accompanied with multiple organ dysfunctions, coexistence of various diseases, complexity of medications, large fluctuations in blood glucose, and frequent hypoglycemia. Both excessive glucose fluctuations and severe hypoglycemia are closely associated with vascular complications. So a new treatment concept for the aged T2DM patients is that, on the basis of blood glucose controlling, we should reduce blood glucose fluctuation and occurrence of severe hypoglycemia, and thus, will reduce the occurrence and the development of chronic complications of T2DM.