Objective To analyze the correlation between the platelet aggregation from thromboelastography (TEG) and light transmission aggregation (LTA) in patients with acute coronary syndrome (ACS) after dual antiplatelet therapy. Methods Ninty-three ACS patients who were prescribed with aspirin and clopidogrel in Institute of Geriatric Cardiology, Chinese PLA General Hospital during September 2010 to September 2012 were subjected in this study. They received LTA and TEG to determine platelet aggregation induced by adenosine diphosphate (ADP) and arachidonic acid (AA). Correlation and regression analysis were applied to analyze the relationship between detection indicators. Results The ADP-induced platelet aggregation were (59.3±21.34)% and (63.67±28.15)% respectively by LTA and TEG, with a correlation coefficient r＝0.814 (P＜0.0001), and the regression equation was ^YLTA＝0.2+0.617XTEG. The AA-induced platelet aggregation were (40.87±35.16)% and (46.02±39.26)% respectively with LTA and TEG with a correlation coefficient r＝0.965(P＜0.0001), and the regression equation was ^YLTA＝1.077XTEG+0.02. Conclusion Platelet function determined by LTA and TEG is in good correlation in ACS patients after dual antiplatelet therapy.