老年肝胆外科手术患者术后肺部并发症与膈肌功能的相关性
作者:
作者单位:

(1.中国人民解放军总医院第二医学中心综合外科,北京100853;2. 中国人民解放军总医院国家老年疾病临床医学研究中心,北京100853)

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R563;R445

基金项目:

中国人民解放军总医院第二医学中心孵化项目(ZXFH2002)


Correlation between postoperative pulmonary complications and diaphragm function in elderly patients undergoing hepatobiliary surgery
Author:
Affiliation:

(1. Department of General Surgery, Second Medical Center, Chinese PLA General Hospital, Beijing 100853, China;2. National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China)

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    摘要:

    目的 分析老年肝胆外科手术患者术后肺部并发症(PPCs)与膈肌功能的关系。方法 收集解放军总医院第二医学中心综合外科行肝胆外科手术的16例老年患者的临床资料。根据术后是否出现肺部并发症分为PPCs组(6例)和非PPCs组(10例)。应用床旁超声分别于术前1天、术后当天、术后第1天、术后第3天及术后第7天监测患者右侧膈肌移动度(DE)。比较2组患者术前DE、术后最小DE、ΔDE、手术时间及手术方式的差异。采用SPSS 23.0统计软件进行数据分析。采用多因素logistic回归分析影响PPCs的危险因素,并绘制受试者工作特征(ROC)曲线评价其对PPCs的预测价值。结果 2组患者术前DE及手术方式比较,差异无统计学意义(P>0.05)。与非PPCs组相比,PPCs组患者手术时间更长[(247.500±68.099)和(162.300±66.111)min]、术后最小DE更小[(1.071±0.202)和(1.414±0.236)cm]、ΔDE更大[(0.536±0.106)和(0.343±0.139)cm],差异均有统计学意义(均P<0.05)。多因素logistic回归分析显示,手术时间及术后最小DE是影响PPCs的独立危险因素。手术时间及术后最小DE预测PPCs的ROC曲线下面积分别为0.825(95%CI 0.670~0.980)和0.867(95%CI 0.693~0.974),最佳截断点分别为210min和1.19cm,灵敏度分别为83.33%和90.00%,特异度分别为80.00%和83.33%。结论 术后膈肌功能下降及长时间手术是影响老年肝胆外科手术患者PPCs的危险因素,可通过膈肌超声监测膈肌功能对PPCs进行预测。

    Abstract:

    Objective To analyze the association between postoperative pulmonary complications (PPCs) and diaphragm function in the elderly patients undergoing hepatobiliary surgery. Methods Clinical data were collected of 16 elderly patients who underwent hepatobiliary surgery at the Department of General Surgery of the Second Medical Center of Chinese PLA General Hospital. According to postoperative pulmonary complications, they were divided into six patients in the PPCs group (n=6) and non-PPCs group (n=10). Bedside ultrasound was used to monitor diaphragmatic mobility (DE) on the right side of the patients on the preoperative day 1 and the postoperative day 1,3, and 7. The two groups were compared in preoperative DE and postoperative minimal DE, ΔDE, operation time, and surgical approach. SPSS 23.0 were used for data analysis and multivariate logistic regression for analysis of the risk factors affecting PPCs. Receiver operating characteristic (ROC) curves were drawn to evaluate their predictive value for PPCs. Results There was no significant difference between the two groups in the preoperative DE and surgical approach (P>0.05). Compared with the non-PPCs group, the PPCs group had longer operation time [(247.500±68.099) vs (162.300±66.111) min], smaller postoperative minimal DE [(1.071±0.202) vs (1.414±0.236) cm] and greater ΔDE [(0.536±0.106) vs (0.343±0.139) cm], the differences being all statistically significant (P<0.05 for all). Multivariate logistic regression analysis revealed that operation time and minimal postoperative DE were independent risk factors for PPCs. The area under the ROC curve for predicting PPCs was 0.825 (95%CI 0.670-0.980) by operation time and 0.867 (95%CI 0.693-0.974) by postoperative minimum DE, and the optimal cut-off points were 210 min and 1.19cm (sensitivity 83.33% vs 90.00%; specificity 80.00% vs 83.33%). Conclusion The decline of diaphragm function after operation and prolonged operation are risk factors affecting PPCs in the elderly patients undergoing major hepatobiliary surgery. PPCs can be predicted by monitoring diaphragm function through ultrasound.

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曹延祥,刘朝阳,程芮.老年肝胆外科手术患者术后肺部并发症与膈肌功能的相关性[J].中华老年多器官疾病杂志,2023,22(2):110~113

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  • 收稿日期:2022-07-26
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  • 在线发布日期: 2023-02-28
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