在线办公
期刊论坛
主 管
解放军总医院
主 办
解放军总医院医学创新研究部、国家老年疾病临床医学研究中心(解放军总医院)、解放军总医院第六医学中心心血管病医学部
编 辑
中华老年多器官疾病杂志编辑委员会
100853, 北京市复兴路28号
电话:010-66936756
传真:010-66936756
E-mail: zhlndqg@mode301.cn
创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
李惠子,王磊,杨永向,关阳,李韵,戴炜,王佳楠.老年人体质量指数和体成分与认知功能的相关性[J].中华老年多器官疾病杂志,2022,21(10):760~765
老年人体质量指数和体成分与认知功能的相关性
Correlation of body mass index and body composition with cognitive function in the elderly
投稿时间:2022-06-08  
DOI:10.11915/j.issn.1671-5403.2022.10.164
中文关键词:  老年人  体质量指数  体成分  认知功能
英文关键词:aged  body mass index  body composition  cognitive function Corresponding author:WANG Jia-Nan,E-mail:wangjianan_wjn@163.com〖FL
基金项目:
作者单位E-mail
李惠子 火箭军特色医学中心 全科医学科, wangjianan_wjn@163.comcorrelation 
王磊 火箭军特色医学中心 门诊部, wangjianan_wjn@163.comcorrelation 
杨永向 火箭军特色医学中心 门诊部, wangjianan_wjn@163.comcorrelation 
关阳 火箭军特色医学中心 全科医学科, wangjianan_wjn@163.comcorrelation 
李韵 火箭军特色医学中心 全科医学科, wangjianan_wjn@163.comcorrelation 
戴炜 火箭军特色医学中心 全科医学科, wangjianan_wjn@163.comcorrelation 
王佳楠 火箭军特色医学中心 全科医学科, wangjianan_wjn@163.comcorrelation 
摘要点击次数: 53
全文下载次数: 33
中文摘要:
      目的 探讨老年人群体质量指数(BMI)、体成分与认知功能的相关性。 方法 选择2021年1月至12月火箭军特色医学中心营养门诊就诊的老年人391例作为研究对象。采用蒙特利尔认知评估(MoCA)量表进行认知评估,分为正常组(≥26分)、轻度组(17~26分)和中重度组(≤17分)。测量身高和体质量并计算BMI,采用多频节段生物电阻抗法得到体成分指标,分析BMI和体成分与认知功能的相关性。以认知功能障碍(CI)诊断分级为因变量,BMI、相关人体成分为自变量,校正生活方式、基础疾病等混杂因素,进行多因素logistic回归分析。采用SPSS 25.0软件进行数据分析。根据数据类型,组间比较分别采用LSD-t检验、方差分析及χ2检验。结果 正常组、轻度组和中重度组间BMI、体脂率(PBF)、腰臀比(WHR)比较,差异均有统计学意义(均P<0.05)。正常组、轻度组和中重度组间BFM、VFA均随认知功能障碍程度的增加而呈现升高趋势[(22.45±4.97)和(26.97±5.54)和(31.10±3.45)kg,(104.42±26.73)和(125.57±29.58)和(177.01±25.26)cm2;均P<0.05],中重度组SLM、SMM、BMR均低于正常组和轻度组[(37.97±8.16)和(48.06±8.00)、(47.70±9.44)kg,(21.42±5.60)和(28.14±5.11)、(28.00±6.04)kg,(1238.95±205.84)和(1469.33±182.12)、(1463.94±215.27)kcal;均P<0.05]。结果显示,与正常体质量组比较,肥胖组CI发生风险较高(OR=2.145,P<0.05);与WHR正常组比较,超标组CI发生风险较高(OR=21.475,P<0.05);与PBF Q1组比较,PBF Q2组、Q3组和Q4组CI发生风险较高(OR=14.324、22.298、39.175,P<0.05);与体脂肪量(BFM)Q1组比较,BFM Q3组和Q4组CI发生风险较高(OR=14.588、26.239,P<0.05)。结论 老年人群BMI、肥胖与认知功能障碍发生存在相关性。
英文摘要:
      Objective To investigate the correlation of body mass index (BMI) and body composition with cognitive function in the elderly population. Methods A total of 391 elderly patients who visited the nutritional clinic of our medical center from January to December 2021 were recruited as the research objects. Montreal Cognitive Assessment (MoCA) scale was used to assess the patients, and according to the results, the patients were divided into normal group (≥26), mild group (17-26) and moderate-severe group (≤17). Their height and weight were measured and BMI was calculated. Multi-frequency bioelectrical impedance analysis (MF-BIA) was used to obtain body composition, and the correlation of BMI and body composition with cognitive function was analyzed. When the diagnostic grade of cognitive impairment (CI) was used as the dependent variable, BMI and related body composition were regarded as the independent variables, multivariate logistic regression analysis was carried out after the adjustment of confounding factors such as hypertension and diabetes. SPSS statistics 25.0 was used for statistical analysis. Data comparison between two groups was performed using LSD-t test, Fisher exact test or χ2test depending on data type. Results There were significant differences in BMI, body fat percentage (PBF) and waist-hip ratio (WHR) among the normal group, mild group and moderate-severe group (P<0.05). The body fat mass (BFM) and visceral fat area (VFA) showed an increasing trend with the increase of the severity of cognitive dysfunction in the 3 groups [(22.45±4.97) vs (26.97±5.54) vs (31.10±3.45) kg; (104.42 ±26.73) vs (125.57±29.58) vs (177.01±25.26) cm2; P<0.05] . The moderate-severe group had significantly lower soft lean mass (SLM), skeletal muscle mass (SMM) and basal metabolic rate (BMR) when compared with the normal and mild groups [(37.97±8.16) vs (48.06±8.00) and (47.70±9.44) kg, (21.42±5.60) vs (28.14±5.11) and(28.00±6.04) kg,(1 238.95±205.84) vs(1 469.33±182.12) and(1 463.94±215.27) kcal; all P<0.05). The results of multivariate logistic regression analysis showed that the obesity group had a higher risk of CI than the normal weight group (OR=2.145, P<0.05); the WHR exceeding standard group showed a higher risk of CI than the normal WHR group (OR=21.475, P<0.05); the PBF Q2, Q3 and Q4 groups had a higher risk of CI when compared with the PBF Q1 group (OR=14.324,22.298 and 39.175; P<0.05); and the BFM Q3 group and Q4 group presented a higher risk of CI than the BFM Q1 group (OR=14.588,26.239; P<0.05). Conclusion BMI and obesity are correlated with the occurrence of cognitive dysfunction in the elderly.
查看全文    下载PDF阅读器
关闭