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解放军总医院
主 办
解放军总医院医学创新研究部、国家老年疾病临床医学研究中心(解放军总医院)、解放军总医院第六医学中心心血管病医学部
编 辑
中华老年多器官疾病杂志编辑委员会
100853, 北京市复兴路28号
电话:010-66936756
传真:010-66936756
E-mail: zhlndqg@mode301.cn
创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
石小天,马清.老年认知衰弱的现况及影响因素[J].中华老年多器官疾病杂志,2022,21(8):581~586
老年认知衰弱的现况及影响因素
Current status and influencing factors of cognitive frailty in the elderly
投稿时间:2022-02-03  
DOI:10.11915/j.issn.1671-5403.2022.08.125
中文关键词:  老年人;住院患者;认知衰弱
英文关键词:aged; inpatients; cognitive frailty This work was supported by the Beijing Health Care Project
基金项目:北京市保健课题(京19-7号)
作者单位E-mail
石小天 首都医科大学附属北京友谊医院老年医学科,北京 100050 maqing3@163.comcurrent 
马清 首都医科大学附属北京友谊医院老年医学科,北京 100050 maqing3@163.comcurrent 
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中文摘要:
      目的 调查住院老年患者认知衰弱的现状并探讨其影响因素。方法 选择2018年1月至2021年5月于首都医科大学附属北京友谊医院老年医学科住院、年龄≥60岁且进行老年综合评估的158例患者为研究对象,根据简易精神状态量表(MMSE)及Fried衰弱表型将患者分为认知衰弱组(34例)和非认知衰弱组(124例),比较2组患者一般资料、化验检查及老年综合评估量表得分情况。采用SPSS 26.0统计软件进行数据分析。根据数据类型,分别采用t检验、秩和检验或χ2检验进行组间比较。应用二元logistic回归分析影响住院患者认知衰弱的因素。结果 与非认知衰弱组比较,认知衰弱组年龄更大,营养状况更差,生活能力依赖程度更严重,差异均有统计学意义(均P<0.05)。二元logistic回归分析显示,高龄(OR=0.921,95%CI 0.847~0.981)、IADL受损(OR=4.611,95%CI 1.725~12.328)及低白蛋白血症(OR=1.127,95%CI 1.007~1.262)是住院老年患者认知衰弱的影响因素。结论 住院老年患者认知衰弱发生率高,医务人员应重视老年综合评估,及时有效地筛查,积极采取措施预防老年人认知衰弱的发生与发展,促进健康老龄化。
英文摘要:
      Objective To investigate the current status and influencing factors of cognitive frailty in the elderly inpatients. Methods A total of 158 elderly patients (≥60 years) receiving comprehensive geriatric assessment in Department of Geriatrics of our hospital from January 2018 to May 2021 were recruited in the study. According to the results of mini-mental state examination (MMSE) and Fried frailty phenotype assessment, the participants were divided into cognitive frail group (n=34) and non-cognitive frail group (n=124). Their general data, results of laboratory tests and scores of comprehensive geriatric assessment were compared between the 2 groups. SPSS statistics 26.0 was used for statistical analysis. Student′s t test, Rank sum test or Chi-square test was employed for intergroup comparison based on different data types. Binary logistic regression analysis was applied to analyze the factors affecting cognitive frailty in hospitalized patients. Results The cognitive frail group had older age, poorer nutritional status, and more dependent on others for daily living when compared with the non-cognitive frail group (all P<0.05). Binary logistic regression analysis showed that older age (OR=0.921,95%CI 0.847-0.981), declined instrumental activities of daily living (OR=4.611,95%CI 1.725-12.328) and hypoalbuminemia (OR=1.127,95%CI 1.007-1.262) were influencing factors of cognitive frailty in the elderly inpatients. Conclusion The prevalence of cognitive frailty is quite high in elderly patients. Clinicians should pay attention to comprehensive geriatric assessment, timely and effective screening, and active measures to prevent the development of cognitive frailty in the elderly in order to promoting the realization of successful aging.
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