Research progress of acute sarcopenia
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(1. Center of Gerontology and Geriatrics, Chengdu 610041, China ;4. National Clinical Research Center for Geriatrics, Chengdu 610041, China;5. Precision Medicine Research Center, Western China Hospital, Sichuan University, Chengdu 610041, China;2. Department of Geriatrics, Hefei Second People′s Hospital, Hefei 230011, China;3. General Department, First People′s Hospital of Longquanyi District, Chengdu 610199, China)

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R592

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    Abstract:

    Acute sarcopenia is defined as sarcopenia lasting less than 6 months and is usually a result of acute stresses (acute disease, surgery, trauma, etc.). The condition, a concept proposed only a few years ago, is a newly recognized and defined syndrome and has not yet recieved much attention in the research community. Acute sarcopenia is strongly associated with poor health-related prognoses, increasing intensive care unit admissions, prolonging mechanical ventilation and hospitalization, and increasing the risk of death. Its diagnosis is based on the diagnostic criteria of sarcopenia combined with acute stresses and the time of onset. To date, few studies focus on acute sarcopenia, and its pathogenesis remains unclear, which is probably related to inflammation, being bedridden, malnutrition, and hormonal levels. Potential interventions for acute sarcopenia include exercise, nutritional interventions, and neuromuscular electrical stimulation, but no therapeutic drugs are available.

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History
  • Received:March 04,2022
  • Revised:
  • Adopted:
  • Online: January 20,2023
  • Published: