Research progress on relationship between intestinal flora and pathogenesis of type 2 diabetes mellitus
Received:November 16, 2021  
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DOI:10.11915/j.issn.1671-5403.2022.09.154
Key words:diabetes mellitus, type 2  intestinal flora  pathogenesis This work was supported by the Project of Science and Technology Plan of Inner Mongolia
Author NameAffiliationE-mail
LIU Yu-Xin First Clinical College, Inner Mongolia Medical University, Hohhot 010110, China antuoya@163.comresearch 
HAN Ying-Xiang First Clinical College, Inner Mongolia Medical University, Hohhot 010110, China antuoya@163.comresearch 
BAO Ai-Ling First Clinical College, Inner Mongolia Medical University, Hohhot 010110, China antuoya@163.comresearch 
WANG Ya-Fei Department of Clinical Laboratory, First Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China antuoya@163.comresearch 
TUO Ya Department of Clinical Laboratory, First Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China antuoya@163.comresearch 
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Abstract:
      Type 2 diabetes mellitus (T2DM) has become a global public health problem. It has attracted much attention due to its increasing incidence rate and complex complications, and serious threats to human health and quality of life. Intestinal flora may be an important factor affecting the occurrence and development of T2DM in addition to genetics and life and diet styles. Its compositions may trigger T2DM by affecting the metabolism of short chain fatty acids and bile acids, endotoxemia and other ways. To reveal the correlation between intestinal flora and the pathogenesis of T2DM, it is suggested that the construction of intestinal flora homeostasis may become a new potential target for the prevention and improvement of T2DM.
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